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Global distribution of malaria-resistant MHC-HLA alleles: the number and frequencies of alleles and malaria risk

BACKGROUND: The major histocompatibility complex (MHC) is the most polymorphic genetic region in vertebrates, but the origin of such genetic diversity remains unresolved. Several studies have demonstrated at the within-population level that individuals harbouring particular alleles can be less or mo...

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Detalhes bibliográficos
Autor principal: Garamszegi, László Zsolt
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162943/
https://ncbi.nlm.nih.gov/pubmed/25187124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-13-349
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