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Inferring copy number and genotype in tumour exome data

BACKGROUND: Using whole exome sequencing to predict aberrations in tumours is a cost effective alternative to whole genome sequencing, however is predominantly used for variant detection and infrequently utilised for detection of somatic copy number variation. RESULTS: We propose a new method to inf...

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Autori principali: Amarasinghe, Kaushalya C, Li, Jason, Hunter, Sally M, Ryland, Georgina L, Cowin, Prue A, Campbell, Ian G, Halgamuge, Saman K
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162913/
https://ncbi.nlm.nih.gov/pubmed/25167919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-732
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