An allosteric switch controls the procoagulant and anticoagulant activities of thrombin.
Thrombin is an allosteric enzyme existing in two forms, slow and fast, that differ widely in their specificities toward synthetic and natural amide substrates. The two forms are significantly populated in vivo, and the allosteric equilibrium can be affected by the binding of effectors and natural su...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.5977 |
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