JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination

Genetic anomalies on the JNK pathway confer susceptibility to autism spectrum disorders, schizophrenia, and intellectual disability. The mechanism whereby a gain or loss of function in JNK signaling predisposes to these prevalent dendrite disorders, with associated motor dysfunction, remains unclear...

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Detalhes bibliográficos
Main Authors: Komulainen, Emilia, Zdrojewska, Justyna, Freemantle, Erika, Mohammad, Hasan, Kulesskaya, Natalia, Deshpande, Prasannakumar, Marchisella, Francesca, Mysore, Raghavendra, Hollos, Patrik, Michelsen, Kimmo A., Mågard, Mats, Rauvala, Heikki, James, Peter, Coffey, Eleanor T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Neuroscience
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162472/
https://ncbi.nlm.nih.gov/pubmed/25309320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00272
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