JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche

Promoting adult hippocampal neurogenesis is expected to induce neuroplastic changes that improve mood and alleviate anxiety. However, the underlying mechanisms remain largely unknown and the hypothesis itself is controversial. Here we show that mice lacking Jnk1, or c-Jun N-terminal kinase (JNK) inh...

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Publicat a:Mol Psychiatry
Autors principals: Mohammad, H, Marchisella, F, Ortega-Martinez, S, Hollos, P, Eerola, K, Komulainen, E, Kulesskaya, N, Freemantle, E, Fagerholm, V, Savontous, E, Rauvala, H, Peterson, B D, van Praag, H, Coffey, E T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2018
Matèries:
Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794884/
https://ncbi.nlm.nih.gov/pubmed/27843149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2016.203
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