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Probing transient protein-mediated DNA linkages using nanoconfinement
We present an analytic technique for probing protein-catalyzed transient DNA loops that is based on nanofluidic channels. In these nanochannels, DNA is forced in a linear configuration that makes loops appear as folds whose size can easily be quantified. Using this technique, we study the interactio...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Institute of Physics
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162420/ https://ncbi.nlm.nih.gov/pubmed/25379073 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4882775 |
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