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Chromatin modification mapping in nanochannels

We report the simultaneous mapping of multiple histone tail modifications on chromatin that has been confined to nanofluidic channels. In these channels, chromatin is elongated, and histone modification can be detected using fluorescently tagged monoclonal antibodies. Using reconstituted chromatin w...

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Bibliografiske detaljer
Main Authors: Lim, Shuang Fang, Karpusenko, Alena, Blumers, Ansel L., Streng, Diana E., Riehn, Robert
Format: Artigo
Sprog:Inglês
Udgivet: AIP Publishing LLC 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855038/
https://ncbi.nlm.nih.gov/pubmed/24396539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4833257
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