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Chromatin modification mapping in nanochannels

We report the simultaneous mapping of multiple histone tail modifications on chromatin that has been confined to nanofluidic channels. In these channels, chromatin is elongated, and histone modification can be detected using fluorescently tagged monoclonal antibodies. Using reconstituted chromatin w...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Lim, Shuang Fang, Karpusenko, Alena, Blumers, Ansel L., Streng, Diana E., Riehn, Robert
Format: Artigo
Sprache:Inglês
Veröffentlicht: AIP Publishing LLC 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3855038/
https://ncbi.nlm.nih.gov/pubmed/24396539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1063/1.4833257
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