Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development

Precise control of self-renewal and differentiation of progenitor cells into the cranial neural crest (CNC) pool ensures proper head development, guided by signaling pathways such as BMPs, FGFs, Shh and Notch. Here, we show that murine Sox2 plays an essential role in controlling progenitor cell beha...

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Detalhes bibliográficos
Main Authors: Mandalos, Nikolaos, Rhinn, Muriel, Granchi, Zoraide, Karampelas, Ioannis, Mitsiadis, Thimios, Economides, Aris N., Dollé, Pascal, Remboutsika, Eumorphia
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162359/
https://ncbi.nlm.nih.gov/pubmed/25309446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00345
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