Sox2 acts as a rheostat of epithelial to mesenchymal transition during neural crest development

Precise control of self-renewal and differentiation of progenitor cells into the cranial neural crest (CNC) pool ensures proper head development, guided by signaling pathways such as BMPs, FGFs, Shh and Notch. Here, we show that murine Sox2 plays an essential role in controlling progenitor cell beha...

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Main Authors: Mandalos, Nikolaos, Rhinn, Muriel, Granchi, Zoraide, Karampelas, Ioannis, Mitsiadis, Thimios, Economides, Aris N., Dollé, Pascal, Remboutsika, Eumorphia
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2014
Teme:
Physiology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162359/
https://ncbi.nlm.nih.gov/pubmed/25309446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00345
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