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Combining a Chip-Mate nESI Ion Source with Make-Up Flow Strategy for Increased System Robustness and Sensitivity in nLC-nESI-MS
Adding a post column stream of solvent to the effluent from a nano-liquid chromatography system (make-up flow strategy, MUF) allows for an optimization of the solvent composition for nano-electrospray (nESI) formation of ions and can positively influence analytical performance by effecting ionizatio...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Association of Biomolecular Resource Facilities
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4162202/ |
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