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Phosphorylation of Cdc42 Effector Protein-4 (CEP4) by Protein Kinase C Promotes Motility of Human Breast Cells

Cdc42 effector protein-4 (CEP4) was recently identified by our laboratory to be a substrate of multiple PKC isoforms in non-transformed MCF-10A human breast cells. The significance of phosphorylated CEP4 to PKC-stimulated motility of MCF-10A cells was evaluated. Single site mutants at Ser residues e...

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Detalhes bibliográficos
Main Authors: Zhao, Xin, Rotenberg, Susan A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162185/
https://ncbi.nlm.nih.gov/pubmed/25086031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.577783
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