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Pyruvate Kinase M2 in Blood Circulation Facilitates Tumor Growth by Promoting Angiogenesis

It is long known that pyruvate kinase isoform M2 (PKM2) is released into the circulation of cancer patients. The PKM2 levels in patients have been suggested as a diagnostic marker for many types of cancers. However, it is not known how PKM2 is released in the blood, and whether the circulating PKM2...

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Autores principales: Li, Liangwei, Zhang, Yinwei, Qiao, Jingjuan, Yang, Jenny J., Liu, Zhi-Ren
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4162182/
https://ncbi.nlm.nih.gov/pubmed/25070887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.576934
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