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Role of the Phagocyte in Host-Parasite Interactions XXVII. Myeloperoxidase-H(2)O(2)-Cl(−)-Mediated Aldehyde Formation and Its Relationship to Antimicrobial Activity

Evidence is presented which suggests that the mechanism of action of the myeloperoxidase-H(2)O(2)-Cl(−) antimicrobial system in the phagocyte is by the formation of aldehydes. Aldehyde production resulting from myeloperoxidase-mediated decarboxylation and deamination of alanine was quantitated with...

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Detalles Bibliográficos
Autores principales: Strauss, R. R., Paul, B. B., Jacobs, A. A., Sbarra, A. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 1971
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC416202/
https://ncbi.nlm.nih.gov/pubmed/16558023
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