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Role of the Phagocyte in Host-Parasite Interactions XXVII. Myeloperoxidase-H(2)O(2)-Cl(−)-Mediated Aldehyde Formation and Its Relationship to Antimicrobial Activity

Evidence is presented which suggests that the mechanism of action of the myeloperoxidase-H(2)O(2)-Cl(−) antimicrobial system in the phagocyte is by the formation of aldehydes. Aldehyde production resulting from myeloperoxidase-mediated decarboxylation and deamination of alanine was quantitated with...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Strauss, R. R., Paul, B. B., Jacobs, A. A., Sbarra, A. J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1971
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC416202/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/16558023/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.3.4.595-602.1971
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