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Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region.

Homozygous deletions have been central to the discovery of several tumor-suppressor genes, but their finding has often been either serendipitous or the result of a directed search. A recently described technique [Lisitsyn, N., Lisitsyn, N. & Wigler, M. (1993) Science 259, 946-951] held out the poten...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Schutte, M, da Costa, L T, Hahn, S A, Moskaluk, C, Hoque, A T, Rozenblum, E, Weinstein, C L, Bittner, M, Meltzer, P S, Trent, J M
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1995
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41619/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7597059/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.13.5950
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