Identification by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region.

Homozygous deletions have been central to the discovery of several tumor-suppressor genes, but their finding has often been either serendipitous or the result of a directed search. A recently described technique [Lisitsyn, N., Lisitsyn, N. & Wigler, M. (1993) Science 259, 946-951] held out the p...

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Main Authors: Schutte, M, da Costa, L T, Hahn, S A, Moskaluk, C, Hoque, A T, Rozenblum, E, Weinstein, C L, Bittner, M, Meltzer, P S, Trent, J M
Format: Artigo
Sprog:Inglês
Udgivet: 1995
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC41619/
https://ncbi.nlm.nih.gov/pubmed/7597059
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