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Neuromyelitis Optica IgG Causes Placental Inflammation and Fetal Death
Neuromyelitis optica (NMO) is an inflammatory demyelinating disease of the CNS and affects women of childbearing age. Most patients with NMO have circulating Abs, termed NMO-IgG, against the astrocytic water channel protein aquaporin-4. In the CNS, NMO-IgG causes complement-mediated astrocyte damage...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161708/ https://ncbi.nlm.nih.gov/pubmed/23935196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301483 |
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