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miR-21 induces cell proliferation and suppresses the chemosensitivity in glioblastoma cells via downregulation of FOXO1

miR-21 shares a potential oncogenic function. The overexpression of miR-21 was common in glioblastoma, which is the most common lethal primary intracranial tumor. The study aimed at miR-21 effect on Glioblastoma cell line A172 of proliferation, apoptosis, and chemosensitivity and its definite mechan...

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Bibliografiske detaljer
Main Authors: Lei, Bing-Xi, Liu, Zheng-Hao, Li, Zhong-Jun, Li, Chao, Deng, Yue-Fei
Format: Artigo
Sprog:Inglês
Udgivet: e-Century Publishing Corporation 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161547/
https://ncbi.nlm.nih.gov/pubmed/25232387
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