Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a

FOXO transcription factors are key tumor suppressors in mammalian cells. Until now, suppression of FOXOs in cancer cells was thought to be mainly due to activation of multiple onco-kinases by a phosphorylation-ubiquitylation-mediated cascade. Therefore, it was speculated that inhibition of FOXO prot...

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Detalhes bibliográficos
Main Authors: Lin, Huanxin, Dai, Ting, Xiong, Huaping, Zhao, Xiaohui, Chen, Xiuting, Yu, Chunping, Li, Jun, Wang, Xi, Song, Libing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009749/
https://ncbi.nlm.nih.gov/pubmed/21203424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015797
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