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Unregulated miR-96 Induces Cell Proliferation in Human Breast Cancer by Downregulating Transcriptional Factor FOXO3a

FOXO transcription factors are key tumor suppressors in mammalian cells. Until now, suppression of FOXOs in cancer cells was thought to be mainly due to activation of multiple onco-kinases by a phosphorylation-ubiquitylation-mediated cascade. Therefore, it was speculated that inhibition of FOXO prot...

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Main Authors: Lin, Huanxin, Dai, Ting, Xiong, Huaping, Zhao, Xiaohui, Chen, Xiuting, Yu, Chunping, Li, Jun, Wang, Xi, Song, Libing
格式: Artigo
語言:Inglês
出版: Public Library of Science 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3009749/
https://ncbi.nlm.nih.gov/pubmed/21203424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015797
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