Helminth Infections Coincident with Active Pulmonary Tuberculosis Inhibit Mono- and Multifunctional CD4(+) and CD8(+) T Cell Responses in a Process Dependent on IL-10

Tissue invasive helminth infections and tuberculosis (TB) are co-endemic in many parts of the world and can trigger immune responses that might antagonize each other. We have previously shown that helminth infections modulate the Th1 and Th17 responses to mycobacterial-antigens in latent TB. To dete...

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Main Authors: George, Parakkal Jovvian, Anuradha, Rajamanickam, Kumar, Nathella Pavan, Sridhar, Rathinam, Banurekha, Vaithilingam V., Nutman, Thomas B., Babu, Subash
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161445/
https://ncbi.nlm.nih.gov/pubmed/25211342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004375
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