Decreased Frequencies of Circulating CD4(+) T Follicular Helper Cells Associated with Diminished Plasma IL-21 in Active Pulmonary Tuberculosis

BACKGROUND: Circulating T follicular helper (Tfh) cells represent a distinct subset of CD4(+) T cells and are important in immunity to infections. Although they have been shown to play a role in experimental models of tuberculosis infection, their role in human tuberculosis remains unexplored. AIMS/...

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Main Authors: Kumar, Nathella Pavan, Sridhar, Rathinam, Hanna, Luke E., Banurekha, Vaithilingam V., Nutman, Thomas B., Babu, Subash
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4208798/
https://ncbi.nlm.nih.gov/pubmed/25343703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0111098
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