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Can Natural Proteins Designed with ‘Inverted’ Peptide Sequences Adopt Native-Like Protein Folds?

We have carried out a systematic computational analysis on a representative dataset of proteins of known three-dimensional structure, in order to evaluate whether it would possible to ‘swap’ certain short peptide sequences in naturally occurring proteins with their corresponding ‘inverted’ peptides...

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Detalhes bibliográficos
Main Authors: Sridhar, Settu, Guruprasad, Kunchur
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161436/
https://ncbi.nlm.nih.gov/pubmed/25210740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0107647
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