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Causal Variation in Yeast Sporulation Tends to Reside in a Pathway Bottleneck

There has been extensive debate over whether certain classes of genes are more likely than others to contain the causal variants responsible for phenotypic differences in complex traits between individuals. One hypothesis states that input/output genes positioned in signal transduction bottlenecks a...

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Bibliographic Details
Main Authors: Lorenz, Kim, Cohen, Barak A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161353/
https://ncbi.nlm.nih.gov/pubmed/25211152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004634
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