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Ganaxolone improves behavioral deficits in a mouse model of post-traumatic stress disorder
Allopregnanolone and its equipotent stereoisomer, pregnanolone (together termed ALLO), are neuroactive steroids that positively and allosterically modulate the action of gamma-amino-butyric acid (GABA) at GABA(A) receptors. Levels of ALLO are reduced in the cerebrospinal fluid of female premenopausa...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Frontiers Media S.A.
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4161165/ https://ncbi.nlm.nih.gov/pubmed/25309317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00256 |
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