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In a mouse model relevant for PTSD, selective brain steroidogenic stimulants (SBSSs) improve behavioral deficits by normalizing allopregnanolone biosynthesis

The pathophysiological role of the neurosteroid 3α-hydroxy-5α-pregnan-20-one (allopregnanolone) in neuropsychiatric disorders has been highlighted in several recent investigations. For instance, allopregnanolone levels are decreased in the cerebrospinal fluid (CSF) of patients with posttraumatic str...

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Kaydedildi:
Detaylı Bibliyografya
Yazar: Pinna, Graziano
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942072/
https://ncbi.nlm.nih.gov/pubmed/20716970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e32833d8ba0
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