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New Synaptic and Molecular Targets for Neuroprotection in Parkinson’s Disease

The defining anatomical feature of Parkinson’s disease (PD) is the degeneration of substantia nigra pars compacta (SNc) neurons, resulting in striatal dopamine (DA) deficiency and in the subsequent alteration of basal ganglia physiology. Treatments targeting the dopaminergic system alleviate PD symp...

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Hlavní autoři: Calabresi, Paolo, Di Filippo, Massimiliano, Gallina, Antongiulio, Wang, Yingfei, Stankowski, Jeannette N., Picconi, Barbara, Dawson, Valina L., Dawson, Ted M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4161019/
https://ncbi.nlm.nih.gov/pubmed/22927178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.25096
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