Screening Methods to Identify TALEN-Mediated Knockout Mice

Genome editing with site-specific nucleases, such as zinc-finger nucleases or transcription activator-like effector nucleases (TALENs), and RNA-guided nucleases, such as the CRISPR/Cas (clustered regularly interspaced short palindromic repeats/CRISPR-associated) system, is becoming the new standard...

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Main Authors: Nakagawa, Yoshiko, Yamamoto, Takashi, Suzuki, Ken-Ichi, Araki, Kimi, Takeda, Naoki, Ohmuraya, Masaki, Sakuma, Tetsushi
Formato: Artigo
Idioma:Inglês
Publicado: Japanese Association for Laboratory Animal Science 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160933/
https://ncbi.nlm.nih.gov/pubmed/24521866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.63.79
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