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Differential Release of β-Amyloid from Dendrite- Versus Axon-Targeted APP
The β-amyloid precursor protein (APP) plays a central role in the pathogenesis of Alzheimer's disease. APP is processed in neurons, but little is known about the relative contributions of presynaptic or postsynaptic compartments to the release of Aβ peptides. To address this issue, we transduce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4160770/ https://ncbi.nlm.nih.gov/pubmed/25209273 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2255-14.2014 |
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