Synthesis of Novel Tylophorine Derivatives and Evaluation of Their Anti-Inflammatory Activity

[Image: see text] We have previously demonstrated that DCB-3503, a tylophorine analogue, has an anti-inflammatory property in murine models for autoimmune diseases. However, its mechanism remains unknown. Here, we have synthesized 34 derivatives of DCB-3503 and investigated their effects on T cells...

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Hauptverfasser: Wen, Ti, Wang, Ziwen, Meng, Xianyi, Wu, Meng, Li, Yangguang, Wu, Xiaoli, Zhao, Liqing, Wang, Puyue, Yin, Zhinan, Li-Ling, Jesse, Wang, Qingmin
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160763/
https://ncbi.nlm.nih.gov/pubmed/25221661
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500255j
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