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Novel Antiproliferative Chimeric Compounds with Marked Histone Deacetylase Inhibitory Activity

[Image: see text] Given our interest in finding potential antitumor agents and in view of the multifactorial mechanistic nature of cancer, in the present work, taking advantage of the multifunctional ligands approach, new chimeric molecules were designed and synthesized by combining in single chemic...

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Bibliographische Detailangaben
Hauptverfasser: Giacomini, Elisa, Nebbioso, Angela, Ciotta, Alfonso, Ianni, Cristina, Falchi, Federico, Roberti, Marinella, Tolomeo, Manlio, Grimaudo, Stefania, Cristina, Antonietta Di, Pipitone, Rosaria Maria, Altucci, Lucia, Recanatini, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160757/
https://ncbi.nlm.nih.gov/pubmed/25221651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000959
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