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G protein coupled receptor signaling complexes in live cells
Classical models of receptor (GPCR) and G protein (Gαβγ) signaling based on biochemical studies have proposed that receptor stimulation results in G protein activation (Gα-GTP) and dissociation of the heterotrimer (Gα-GTP + Gβγ) to regulate downstream signaling events. Unclear is whether or not ther...
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Landes Bioscience
2014
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4160338/ https://ncbi.nlm.nih.gov/pubmed/25279251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cl.29392 |
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