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The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration
BACKGROUND: The teleost Astyanax mexicanus is a single species consisting of eyed surface-dwelling (surface fish) and blind cave-dwelling (cavefish) morphs. Cavefish eyes are lost through apoptosis of the lens, which in turn promotes the degeneration of other optic tissues. The αA-crystallin (αA-cry...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4160140/ https://ncbi.nlm.nih.gov/pubmed/25210614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9139-5-28 |
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