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The role of a lens survival pathway including sox2 and αA-crystallin in the evolution of cavefish eye degeneration

BACKGROUND: The teleost Astyanax mexicanus is a single species consisting of eyed surface-dwelling (surface fish) and blind cave-dwelling (cavefish) morphs. Cavefish eyes are lost through apoptosis of the lens, which in turn promotes the degeneration of other optic tissues. The αA-crystallin (αA-cry...

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Detalhes bibliográficos
Main Authors: Ma, Li, Parkhurst, Amy, Jeffery, William R
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160140/
https://ncbi.nlm.nih.gov/pubmed/25210614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9139-5-28
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