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Decreased DJ-1 Leads to Impaired Nrf2-Regulated Antioxidant Defense and Increased UV-A–Induced Apoptosis in Corneal Endothelial Cells

PURPOSE. To investigate the role of DJ-1 in Nrf2-regulated antioxidant defense in corneal endothelial cells (CECs) at baseline and in response to ultraviolet A (UV-A)–induced oxidative stress. METHODS. DJ-1–deficient CECs were obtained by transfection of an immortalized normal human corneal endothel...

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Detaylı Bibliyografya
Asıl Yazarlar: Liu, Cailing, Chen, Yuming, Kochevar, Irene E., Jurkunas, Ula V.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Association for Research in Vision and Ophthalmology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4160071/
https://ncbi.nlm.nih.gov/pubmed/25082883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14580
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