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Decreased DJ-1 Leads to Impaired Nrf2-Regulated Antioxidant Defense and Increased UV-A–Induced Apoptosis in Corneal Endothelial Cells
PURPOSE. To investigate the role of DJ-1 in Nrf2-regulated antioxidant defense in corneal endothelial cells (CECs) at baseline and in response to ultraviolet A (UV-A)–induced oxidative stress. METHODS. DJ-1–deficient CECs were obtained by transfection of an immortalized normal human corneal endothel...
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| Hoofdauteurs: | , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
The Association for Research in Vision and Ophthalmology
2014
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4160071/ https://ncbi.nlm.nih.gov/pubmed/25082883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.14-14580 |
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