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The emerging role of guanine nucleotide exchange factors in ALS and other neurodegenerative diseases
Small GTPases participate in a broad range of cellular processes such as proliferation, differentiation, and migration. The exchange of GDP for GTP resulting in the activation of these GTPases is catalyzed by a group of enzymes called guanine nucleotide exchange factors (GEFs), of which two classes:...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159981/ https://ncbi.nlm.nih.gov/pubmed/25309324 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2014.00282 |
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