Simvastatin Attenuates the Oxidative Stress, Endothelial Thrombogenicity and the Inducibility of Atrial Fibrillation in a Rat Model of Ischemic Heart Failure

Increased atrial oxidative stress has an important role in inducing and maintaining atrial fibrillation (AF), and the activation of the small GTPase Rac1 contributes to the oxidative stress. We investigated the relationship of Rac1, atrial endothelial thromboprotective markers and AF inducibility an...

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Bibliografiske detaljer
Main Authors: Cho, Kyoung-Im, Koo, Sang-Ho, Cha, Tae-Joon, Heo, Jung-Ho, Kim, Hyun-Su, Jo, Gee-Bum, Lee, Jae-Woo
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159883/
https://ncbi.nlm.nih.gov/pubmed/25153633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150814803
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