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Simvastatin Attenuates the Oxidative Stress, Endothelial Thrombogenicity and the Inducibility of Atrial Fibrillation in a Rat Model of Ischemic Heart Failure

Increased atrial oxidative stress has an important role in inducing and maintaining atrial fibrillation (AF), and the activation of the small GTPase Rac1 contributes to the oxidative stress. We investigated the relationship of Rac1, atrial endothelial thromboprotective markers and AF inducibility an...

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Detalhes bibliográficos
Main Authors: Cho, Kyoung-Im, Koo, Sang-Ho, Cha, Tae-Joon, Heo, Jung-Ho, Kim, Hyun-Su, Jo, Gee-Bum, Lee, Jae-Woo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159883/
https://ncbi.nlm.nih.gov/pubmed/25153633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150814803
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