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Rapamycin-Induced Apoptosis in HGF-Stimulated Lens Epithelial Cells by AKT/mTOR, ERK and JAK2/STAT3 Pathways

Hepatocyte growth factor (HGF) induced the proliferation of lens epithelial cells (LECs) and may be a major cause of posterior capsule opacification (PCO), which is the most frequent postoperative complication of cataract surgery. To date, several agents that can block LECs proliferation have been s...

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Detalhes bibliográficos
Main Authors: Tian, Fang, Dong, Lijie, Zhou, Yu, Shao, Yan, Li, Wenbo, Zhang, Hong, Wang, Fei
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159827/
https://ncbi.nlm.nih.gov/pubmed/25116684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150813833
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