Chikusetsu Saponin V Attenuates MPP(+)-Induced Neurotoxicity in SH-SY5Y Cells via Regulation of Sirt1/Mn-SOD and GRP78/Caspase-12 Pathways

Studies have shown that saponins from Panax japonicus (SPJ) possess neuroprotective effects. However, whether Chikusetsu saponin V (CsV), the most abundant member of SPJ, can exert neuroprotective effects against 1-methyl-4-phenylpyridinium ion (MPP(+))-induced cytotoxicity is not known. In this stu...

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Main Authors: Yuan, Ding, Wan, Jing-Zhi, Deng, Li-Li, Zhang, Chang-Cheng, Dun, Yao-Yan, Dai, Yan-Wen, Zhou, Zhi-Yong, Liu, Chao-Qi, Wang, Ting
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159789/
https://ncbi.nlm.nih.gov/pubmed/25073091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms150813209
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