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Novel RNA hybridization method for the in situ detection of ETV1, ETV4 and ETV5 gene fusions in prostate cancer

The genetic basis of 50–60% of prostate cancer is attributable to rearrangements in ETS (ERG, ETV1, ETV4, and ETV5), BRAF and RAF1 genes and overexpression of SPINK1. The development and validation of reliable detection methods are warranted to classify various molecular subtypes of prostate cancer...

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Main Authors: Kunju, Lakshmi Priya, Carskadon, Shannon, Siddiqui, Javed, Tomlins, Scott A, Chinnaiyan, Arul M, Palanisamy, Nallasivam
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159774/
https://ncbi.nlm.nih.gov/pubmed/25203299
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/PAI.0000000000000095
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