CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

Amplification of the C19MC oncogenic miRNA cluster and high LIN28 expression has been linked to a distinctly aggressive group of cerebral CNS-PNETs (group 1 CNS-PNETs) arising in young children. In this study, we sought to evaluate the diagnostic specificity of C19MC and LIN28, and the clinical and...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Spence, Tara, Sin-Chan, Patrick, Picard, Daniel, Barszczyk, Mark, Hoss, Katharina, Lu, Mei, Kim, Seung-Ki, Ra, Young-Shin, Nakamura, Hideo, Fangusaro, Jason, Hwang, Eugene, Kiehna, Erin, Toledano, Helen, Wang, Yin, Shi, Qing, Johnston, Donna, Michaud, Jean, La Spina, Milena, Buccoliero, Anna Maria, Adamek, Dariusz, Camelo-Piragua, Sandra, Peter Collins, V., Jones, Chris, Kabbara, Nabil, Jurdi, Nawaf, Varlet, Pascale, Perry, Arie, Scharnhorst, David, Fan, Xing, Muraszko, Karin M., Eberhart, Charles G., Ng, Ho-Keung, Gururangan, Sridharan, Van Meter, Timothy, Remke, Marc, Lafay-Cousin, Lucie, Chan, Jennifer A., Sirachainan, Nongnuch, Pomeroy, Scott L., Clifford, Steven C., Gajjar, Amar, Shago, Mary, Halliday, William, Taylor, Michael D., Grundy, Richard, Lau, Ching C., Phillips, Joanna, Bouffet, Eric, Dirks, Peter B., Hawkins, Cynthia E., Huang, Annie
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2014
Fag:
Original Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159569/
https://ncbi.nlm.nih.gov/pubmed/24839957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1291-1
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker