CNS-PNETs with C19MC amplification and/or LIN28 expression comprise a distinct histogenetic diagnostic and therapeutic entity

Amplification of the C19MC oncogenic miRNA cluster and high LIN28 expression has been linked to a distinctly aggressive group of cerebral CNS-PNETs (group 1 CNS-PNETs) arising in young children. In this study, we sought to evaluate the diagnostic specificity of C19MC and LIN28, and the clinical and...

সম্পূর্ণ বিবরণ

সংরক্ষণ করুন:
গ্রন্থ-পঞ্জীর বিবরন
প্রধান লেখক: Spence, Tara, Sin-Chan, Patrick, Picard, Daniel, Barszczyk, Mark, Hoss, Katharina, Lu, Mei, Kim, Seung-Ki, Ra, Young-Shin, Nakamura, Hideo, Fangusaro, Jason, Hwang, Eugene, Kiehna, Erin, Toledano, Helen, Wang, Yin, Shi, Qing, Johnston, Donna, Michaud, Jean, La Spina, Milena, Buccoliero, Anna Maria, Adamek, Dariusz, Camelo-Piragua, Sandra, Peter Collins, V., Jones, Chris, Kabbara, Nabil, Jurdi, Nawaf, Varlet, Pascale, Perry, Arie, Scharnhorst, David, Fan, Xing, Muraszko, Karin M., Eberhart, Charles G., Ng, Ho-Keung, Gururangan, Sridharan, Van Meter, Timothy, Remke, Marc, Lafay-Cousin, Lucie, Chan, Jennifer A., Sirachainan, Nongnuch, Pomeroy, Scott L., Clifford, Steven C., Gajjar, Amar, Shago, Mary, Halliday, William, Taylor, Michael D., Grundy, Richard, Lau, Ching C., Phillips, Joanna, Bouffet, Eric, Dirks, Peter B., Hawkins, Cynthia E., Huang, Annie
বিন্যাস: Artigo
ভাষা:Inglês
প্রকাশিত: Springer Berlin Heidelberg 2014
বিষয়গুলি:
Original Paper
অনলাইন ব্যবহার করুন:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159569/
https://ncbi.nlm.nih.gov/pubmed/24839957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-014-1291-1
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