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Outcome-adaptive randomization for a delayed outcome with a short-term predictor: imputation-based designs

Delay in the outcome variable is challenging for outcome-adaptive randomization, as it creates a lag between the number of subjects accrued and the information known at the time of the analysis. Motivated by a real-life pediatric ulcerative colitis trial, we consider a case where a short-term predic...

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Detalhes bibliográficos
Main Authors: Kim, Mi-Ok, Liu, Chunyan, Hu, Feifang, Lee, J. Jack
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159410/
https://ncbi.nlm.nih.gov/pubmed/24889540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6222
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