Inflammation-induced effector CD4(+) T cell interstitial migration is alpha-(v) integrin dependent

Leukocytes must traverse inflamed tissues to effectively control local infection. Although motility in dense tissues appears to be integrin-independent actin-myosin based, during inflammation changes to the extracellular matrix (ECM) may necessitate distinct motility requirements. Indeed, we found t...

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Autores principales: Overstreet, Michael G., Gaylo, Alison, Angermann, Bastian, Hughson, Angela, Hyun, Young-min, Lambert, Kris, Acharya, Mridu, Billroth-Maclurg, Alison C., Rosenberg, Alexander F., Topham, David J., Yagita, Hideo, Kim, Minsoo, Lacy-Hulbert, Adam, Meier-Schellersheim, Martin, Fowell, Deborah J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159184/
https://ncbi.nlm.nih.gov/pubmed/23933892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2682
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