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HDL and Sphingosine-1-phosphate Activate Stat3 in Prostate Cancer DU145 Cells via ERK1/2 and S1P Receptors, and Promote Cell Migration and Invasion
BACKGROUND: Androgen deprivation therapy in men with prostate cancer leads to a significant increase of HDL, but the effect of HDL on prostate cancer is unknown. Recently, HDL, which transports sphingosine-1-phosphate (S1P), was reported to activate Signal transducer and activator of transcription 3...
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| Главные авторы: | , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4159087/ https://ncbi.nlm.nih.gov/pubmed/20979115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21285 |
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