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In vitro reconstitution of a highly processive recombinant human dynein complex

Cytoplasmic dynein is an approximately 1.4 MDa multi-protein complex that transports many cellular cargoes towards the minus ends of microtubules. Several in vitro studies of mammalian dynein have suggested that individual motors are not robustly processive, raising questions about how dynein-associ...

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Bibliografische gegevens
Hoofdauteurs: Schlager, Max A, Hoang, Ha Thi, Urnavicius, Linas, Bullock, Simon L, Carter, Andrew P
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158905/
https://ncbi.nlm.nih.gov/pubmed/24986880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488792
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