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In vitro reconstitution of a highly processive recombinant human dynein complex
Cytoplasmic dynein is an approximately 1.4 MDa multi-protein complex that transports many cellular cargoes towards the minus ends of microtubules. Several in vitro studies of mammalian dynein have suggested that individual motors are not robustly processive, raising questions about how dynein-associ...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BlackWell Publishing Ltd
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4158905/ https://ncbi.nlm.nih.gov/pubmed/24986880 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488792 |
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