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In vitro reconstitution of a highly processive recombinant human dynein complex

Cytoplasmic dynein is an approximately 1.4 MDa multi-protein complex that transports many cellular cargoes towards the minus ends of microtubules. Several in vitro studies of mammalian dynein have suggested that individual motors are not robustly processive, raising questions about how dynein-associ...

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Autors principals: Schlager, Max A, Hoang, Ha Thi, Urnavicius, Linas, Bullock, Simon L, Carter, Andrew P
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158905/
https://ncbi.nlm.nih.gov/pubmed/24986880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488792
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