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In vitro reconstitution of a highly processive recombinant human dynein complex

Cytoplasmic dynein is an approximately 1.4 MDa multi-protein complex that transports many cellular cargoes towards the minus ends of microtubules. Several in vitro studies of mammalian dynein have suggested that individual motors are not robustly processive, raising questions about how dynein-associ...

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Detalhes bibliográficos
Main Authors: Schlager, Max A, Hoang, Ha Thi, Urnavicius, Linas, Bullock, Simon L, Carter, Andrew P
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158905/
https://ncbi.nlm.nih.gov/pubmed/24986880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201488792
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