Interleukin-17+CD8+ T Cells Are Enriched in the Joints of Patients With Psoriatic Arthritis and Correlate With Disease Activity and Joint Damage Progression

OBJECTIVE: Psoriatic arthritis (PsA) is associated with HLA class I genes, in contrast to the association with HLA class II in rheumatoid arthritis (RA). Since IL-17+ cells are considered important mediators of synovial inflammation, we sought to determine whether IL-17–producing CD8+ T cells may be...

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Bibliographic Details
Main Authors: Menon, Bina, Gullick, Nicola J, Walter, Gina J, Rajasekhar, Megha, Garrood, Toby, Evans, Hayley G, Taams, Leonie S, Kirkham, Bruce W
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2014
Subjects:
Spondyloarthritis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158887/
https://ncbi.nlm.nih.gov/pubmed/24470327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38376
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