Cerium oxide nanoparticles protect against Aβ-induced mitochondrial fragmentation and neuronal cell death

Evidence indicates that nitrosative stress and mitochondrial dysfunction participate in the pathogenesis of Alzheimer's disease (AD). Amyloid beta (Aβ) and peroxynitrite induce mitochondrial fragmentation and neuronal cell death by abnormal activation of dynamin-related protein 1 (DRP1), a larg...

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Detalles Bibliográficos
Main Authors: Dowding, J M, Song, W, Bossy, K, Karakoti, A, Kumar, A, Kim, A, Bossy, B, Seal, S, Ellisman, M H, Perkins, G, Self, W T, Bossy-Wetzel, E
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Original Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158687/
https://ncbi.nlm.nih.gov/pubmed/24902900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.72
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