Lhx2 regulates bone remodeling in mice by modulating RANKL signaling in osteoclasts

The LIM homeobox 2 (Lhx2) transcription factor Lhx2 has a variety of functions, including neural induction, morphogenesis, and hematopoiesis. Here we show the involvement of Lhx2 in osteoclast differentiation. Lhx2 was strongly expressed in osteoclast precursor cells but its expression was significa...

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Autors principals: Kim, J H, Youn, B U, Kim, K, Moon, J B, Lee, J, Nam, K-I I, Park, Y-W, O'Leary, D D M, Kim, K K, Kim, N
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2014
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158686/
https://ncbi.nlm.nih.gov/pubmed/24902903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2014.71
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