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Role of Akt and mammalian target of rapamycin in functional outcome after concussive brain injury in mice

Akt (protein kinase B) and mammalian target of rapamycin (mTOR) have been implicated in the pathogenesis of cell death and cognitive outcome after cerebral contusion in mice; however, a role for Akt/mTOR in concussive brain injury has not been well characterized. In a mouse closed head injury (CHI)...

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Main Authors: Zhu, Xiaoxia, Park, Juyeon, Golinski, Julianne, Qiu, Jianhua, Khuman, Jugta, Lee, Christopher CH, Lo, Eng H, Degterev, Alexei, Whalen, Michael J
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4158669/
https://ncbi.nlm.nih.gov/pubmed/24938400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2014.113
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